Mortemus研究发现,癫痫猝死的患者通常处于俯卧位(也就是“趴着”)。芝加哥大学的JamesTao医师也发现(Neurology,):70%的癫痫性猝死与俯卧体位有关。因此,避免癫痫大发作后的俯卧位对预防癫痫猝死非常重要。
然而,仅在睡觉的时候避免俯卧体位是不够的。最近浙大二院癫痫中心与芝加哥大学癫痫中心联合开展了一项研究,观察了癫痫监测病房中癫痫大发作前后患者的体位变化,发现1.6%的患者在扭转性运动中转变为俯卧位。
因此,对于出现癫痫大发作的患者,夜间的发作监测和看护,及时纠正体是非常重要的。如果患者独居,在癫痫大发作前存在扭转运动,他们使用癫痫发作的报警装备(录像监控或者癫痫报警手环)可能能够挽救生命。
文章详见:
Wangetal.,Theincidenceofperi-ictalpronepositioninpatientswithgeneralizedconvulsiveseizures,EpilepsyandBehavior,.
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AbstractObjectiveTheobjectivesofthisstudyweretodeterminetheincidenceofperi-ictalpronepositioninpatientswithgeneralizedconvulsiveseizures(GCS)andtofurtherassesstheriskofsuddenunexpecteddeathinepilepsy(SUDEP)associatedwiththeproneposition.
MethodWeretrospectivelyreviewedthevideo-EEGdataofGCSinpatientswhounderwentlong-termvideo-EEGmonitoringintwoepilepsycenters.Wedeterminedtheperi-ictal(preictal,ictal,and/orpostictal)bodypositions.
ResultsAperi-ictalpronepositionwasobservedin12(6.2%)ofpatientsand13(.2%)ofGCS.In5(1.6%)ofGCS,patientsinnonpronepositionsatseizureonsetturnedintothepronepositionduringversiveseizures.In8(2.6%)ofGCS,patientsweresleepingproneatseizureonset.Peri-ictalinterventionwithbodyrepositioningwasprovidedin11of12patientsand12ofthe13GCS.Repositioningwasnotprovidedduringtheremainingseizure;thepatientdiedintheproneposition.Inthesubsetof96GCSwithoutictalintervention,patientsinasupinepositionatseizureonsetremainedinthesupinepositionatseizureterminationin57(98.3%)of58GCS.Patientssleepingproneatseizureonsetremainedinthepronepositionatseizureterminationin(80%)of5GCS.
ConclusionOurdatasuggestthattheincidenceofperi-ictalpronepositioninpatientswithGCSislow.Bothpronesleepingandforcedictalversionmayresultinpostictalproneposition.AlthoughavoidingpronesleepingmayreducetheSUDEPrisk,influencingforcedictalversionmaybedifficultintheabsenceofsupervision.
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